Slaying Potions and Sigils only affect Power damage

FractalTimePotionSigilDetails
AetherbladeDay Scarlet’s Armies for everything until you reach the Boss room.

Inquest Slaying for Frizz & the Golems

Aquatic RuinsDay Both Potions and the Sigil only work on the Kraits at the start
Chaos IslesDayNo special potions for this fractal
CliffsideDay
Captain Mai TrinDay
Molten BossDay
Molten FurnaceDay
NightmareDay The Krait slaying potions only works on Siax and Ensolyss while Scarlet’s Armies works on all three bosses.

Serpent Slaying Sigil only works on Siax and Ensolyss

Shattered ObservatoryDay Scarlet’s army only works on arkk
SnowblindNight Svanir Slaying Potions works on the Svanirs at the first Event and the Endboss.

Sigil of Wrath works on the Svanirs at the first Event and the Endboss.

Elemental / Demon Slaying works on the Ice Elemental Boss and the small Ice Elementals on the End Boss

Demon Slaying Potions and Sigils work on Elementals

Solid OceanNightNo special potions for this fractal
SwamplandNightNo special potions for this fractal
Thaumanova ReactorDayNo special potions for this fractal
UncategorizedDay Flame Legion Slaying / Smothering Sigil works only on the Fire Shaman

Outlaw Slaying / Justice Sigil only works on the Veteran Bandit Saboteur

Inquest Slaying / Mad Scientist Sigil only works for Old Tom & the 4 Golems at the end

Underground FacilityNight Dredge Slaying / Sorrow Sigil word for all the Dredge and the Dredge Endboss

Elemental Slaying / Demon Slaying Potions and Sigils work on the Ice Elemental endboss

Demon Slaying Potions and Sigils work on Elementals

Urban BattlegroundDayNo special potions for this fractal
VolcanicNight Grawl Slaying Sigil and Potion works on the Grawls at the beginning and the middle event.

Elemental / Demon Slaying Sigil and Potions works on the Endboss and the Lava Slublings

Demon Slaying Potions and Sigils work on Elementals

Fractal Potions
All 3 Potions effects in 1
Gives you 15% dmg and 15% condi dmg + 225 Precision (1 Agony resistance grants 1.5 Precision)
Gives you 50% endurance Recharge and 25% Movement Speed + 225 Concentration (1 Agony resistance grants 1.5 Concentration)
Gives you a 25% dmg reduction + 225 Toughness (1 Agony resistance grants 1.5 Toughness)
Gives you 15 Agony resistance ( use it as a way to reach 150 AR to save some gold or for extra stats as 1 AR = 1.5 of a stat)
Some effects like the 1 AR = 1.5 of a stat only work if you have the fractal mastery Mistlock Singularities

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